Ruptures of delight? A new mouse model of plaque rupture.

There is a strange discrepancy in the world of vascular biology. It is clear from many investigations that the rupture of an atherosclerotic plaque is the most common triggering event for occlusive thrombus formation in a coronary artery, leading to myocardial infarction. However, many large vascular biology meetings do not include specific sessions on this topic. Indeed, even flagship journals such as Arteriosclerosis, Thrombosis, and Vascular Biology do not list “plaque rupture” among the standard keywords to be used during manuscript submission. Why does an issue of such clinical importance have such a low profile?